Catnip Herb – Some Useful Advanced Information
What Is Catnip?
Nepeta cataria L. is the scientific name for this plant.
One of the most common names for catnip is “catmint.”
Catnip, a perennial herb native to central Europe, has become established in the northeastern United States and Canada. The plant has dark green, oval-toothed leaves that reach about 1 m in height. The dried leaves and white blooming tips of the plant contain the plant's therapeutic properties.
The scientific name for this term (s)
Plants in the Lamiaceae family include: Nepeta cataria L. (mint family)
Noun Form (s).
There are several other names for catnip, including cat herb, catnip, and catnip.
An ethnobotanical application.
In a wide variety of cuisines, they can be used as a flavouring ingredient, from soup to stew to various patent beverages and fruit-based liqueurs. The earliest evidence dates back to 1735. the usage of catnip leaves and flowers in herbal drinks was reported. As a diaphoretic, a sedative, and an appetite stimulant, the herb was also used to alleviate gastrointestinal spasms and indigestion. As well as treating diarrhoea and colic, the herb has also been used to treat colds and even cancer. Catnip tea was traditionally used in Appalachia to cure nervousness, stomach problems, rashes, and colds. For respiratory illnesses, dried leaves were smoked, and a poultice was put on the affected area. Flowers and leaves were used to delay menstruation in the early 1900s. According to legend, catnip was smoked in the 1960s because of its euphoric properties.
Catnip has been found to contain more than 20 different chemicals, which might vary greatly depending on the blooming season and location. There are numerous sesquiterpenes and monoterpenes present in the plant, and gas chromatography and nuclear magnetic resonance spectroscopy have found nepetalactone and beta-caryophyllenes.
Nepetalactone, like valerian's valepotriates, may have the essential cat-suppressant function. Most of the catnip essential oil's significant ingredients have been determined to include citronellyl acetate and citronellol. It also contains additional ingredients such as camphor and thymol and other compounds such as carvacrol and nerol.
Studies in mice found that acute and repeated administration of apolar or polar catnip extracts (48 mg/kg/day) for seven days had antidepressant, antianxiety, and motor effects, respectively. An enriched diet reduced the amount of time a patient was unable to move. These results were comparable to those in animals treated with antidepressant fluoxetine; the apolar extract reduced locomotor activity, rising frequency, and immobility duration in the outside test. The behavioural despair test demonstrated that mice administered with the apoland extract had a reduced immobility time. In addition, the apolar extract reduced the time it took for the first immobilisation. Catnip-enriched diet and apolar extract may have antidepressant qualities, according to the results of the study. Antidepressant effects were observed in male rats fed diets enhanced with 10% N. cataria leaves for four hours.
In vitro research
Flavonoids were used to treat the A549 non-small cell lung cancer cell line treated with flavonoids isolated from N. cataria L. in an in vitro investigation. The anticancer impact increased due to increased apoptosis and necrosis rates in A549 cells as a result of rising flavonoid concentration. VEGFR and PI3K mRNA levels were reduced in A549 cells in the therapy group, but PTEN levels increased. As PI3K protein levels climbed, AKT, cyclin B1 and Bcl-2 declined. According to these findings, N. cataria L. flavonoid extracts may inhibit lung cancer via influencing the PTEN/PI3K/AKT pathway.
In vitro and animal studies.
Insecticide and herbicide properties have been researched for catnip nepetalactone and iridoids. Catnip oil has been tested for its ability to repel mosquitoes, black flies, stable flies, and deer ticks in field tests in the United States (Bernier 2005, Feaster 2009). Diethyltoluamide's attraction inhibition is higher (DEET). Catnip oil components were more effective in vitro at deterring yellow fever mosquitoes (Aedes aegypti L.) than a control. When it came to Chauhan in 2005, At doses of 2 mg and 20 mg of catnip, houseflies, stable fly, and filth flies were effectively deterred. The year 2009 belongs to Zhu. Catnip oil-treated filter paper and wax-based catnip pellets (32 mg per pellet) put to waste areas of cow pastures both had a repelling effect on houseflies. Zhu, 2010, p. Another study tested the repelling effect of catnip oil on predators using three different concentrations (0.2, 2 and 20 mg). When repelling stable insects off a person's body, catnip oil proved to be more effective than DEET, with the most significant amount giving the best protection. Using cloths treated with 100 mg catnip oil for six hours, only a few eggs were deposited, showing an egg-laying deterrent effect. Catnip oil concentrations of 15% and 30% were employed in the study's field testing to repel stable flies. It was shown that 500 mg of encapsulated catnip oil strongly inhibited the ability of fly oviposition to persist in oviposition cups. Catnip oil capsules reduced the number of eggs laid on the larval medium of stable flies by 85 per cent and more than 98 per cent, respectively. It was Zhu's year. Horn flies were repelled for six hours by a 20 mg catnip oil dosage in a lab setting. Using 15 per cent catnip oil, cattle were able to repel horn flies successfully.
Catnip N. cataria (CNC) and Rhizoma coptidis (RC) were fed orally to rabbits. Berberine, an alkaloid found in Rhizoma coptidis, was more easily absorbed and released by CNC. Coptisine, palmatine, and epiberberine's bioavailability were reduced. CNC may also reduce Epiberberine concentrations in plasma. Various alkaloids may have different effects due to CNC micro powder that can adsorb the alkaloids and prolong their retention in the small intestine.
As a result of
The conjunctiva on the upper and lower eyelids became irritated within 24 hours of therapy with 0.1 ml catnip oil. 0.5 mL of undiluted catnip oil was given to rabbits for 14 days of research as well. During the evaluation period, all rabbits acquired redness from day 3 to day 4.
Catnip oil has a fatal dosage of 1,300 mg/kg intraperitoneally, according to a recent study.
In 2002, Duke University Catnip misuse did not usually lead to severe bodily repercussions. However, there have been reports of minor symptoms, such as a headache and lethargy. A large amount of tea might cause vomiting if consumed in excess. Toxic effects on the skin, eyes, and dermis were evaluated in mice, rats, and rabbits in a study that included acute oral and dermal toxicities and primary sensitization. A daily dose of 1,000 to 10,000 mg/kg of catnip oil was provided orally for 14 days. At dosages of 1,000 to 2,150 mg/kg, there were no toxicities, except one fatality. A dose of 4,640 mg/kg or above resulted in a 100% death rate. Acute inhalation studies in mice exposed for 2 hours, topical research in which 5,000 mg/kg was administered to the shorn back of rats, Catnip oil administered to the upper and lower eyelids of rabbits for 14 days had no detrimental impact on the animals' eyes.
N. cataria leaf supplementation in the food of male rats for four hours improved their sexual behaviour and performance, as evidenced by a reduction of ascents preceding ejaculatory ascents as well as a rise in the frequency of apomorphine-induced penile erection. Apomorphine-induced penile erection is enhanced by N. cataria, which shows that the active components have dopaminergic properties.
A wide range of uses
Catnip's usage as a human insecticide is the only clinical evidence to justify its use for humans.
How much should I take?
Catnip dose has never been studied in a therapeutic setting. A typical sedative dosage is 4 grammes of the dry herb, commonly taken as a tea. Insect repellent lotion containing 15% essential oil has been utilized.